- Dinamo Moscow 3 - 1 Anderlecht
Agregat 3-1
- Zenit St. Petersburg 3 - 0 PSV Eindhoven
Agregat 4-0
- Besiktas * 1 - 0 Liverpool
Agregat 1-1 tetapi Besiktas yang lolos karena menang 5-4 dalam drama adu penalti
- Borussia Moenchengladbach 2 - 3 Sevilla
Agregat 2-4
- Dynamo Kyiv 3 - 1 Guingamp
Agregat 4-3
- Fiorentina 2 - 0 Tottenham Hotspur
Agregat 3-2
- Inter Milan 1 - 0 Celtic
Agregat 4-3
- Legia Warszawa 0 - 3 Ajax
Agregat 0-4
- Salzburg 1 - 3 Villarreal
Agregat 2-5
- Athletic Bilbao 2 - 3 Torino
Agregat 4-5
- Club Brugge 3 - 0 AaB
Agregat 6-1
- Everton 3 - 1 Young Boys
Agregat 7-2
- Feyenoord 1 - 2 Roma
Agregat 2-3
- Olympiakos 2 - 2 Dnipro
Agregat 2-4
- Napoli 1 - 0 Trabzonspor
Agregat 5-0
- Sporting CP 0 - 0 Wolfsburg
Agregat 0-2