AaB 1-3 Club Brugge
Gol: Nicklas Helenius 71' (pen) - Obbi Oulare 25', Lior Rafaelov 29', Kenneth Emil Petersen 61' (og)
Dnipro 2-0 Olympiakos
Gol: Jaba Kankava 50', Ruslan Rotan 54'
PSV Eindhoven 0-1 Zenit St. Petersburg
Gol: Hulk 64'
AS Roma 1-1 Feyenoord
Gol: Gervinho 22' - Kazim Kazim-Richards 55'
Torino 2-2 Athletic Bilbao
Gol: Maxi Lopez 18', 42' - Inaki Williams 9', Carlos Gurpegi 73'
Tabzonspor 0-4 SSC Napoli
Gol: Henrique 6', Gonzalo Higuain 20', Manolo Gabbiadini 27', Duvan Zapata 90
Wolfsburg 2-0 Sporting CP
Gol: Bas Dost 46', 63'
Young Boys 1-4 Everton
Gol: Guillaume Hoarau 10' - Romelu Lukaku 24', 39', 58', Seamus Coleman 28'
Kartu merah: John Stones 63' (Everton)
Ajax 1-0 Legia Warszawa
Gol: Arkadiusz Milik 35'
Anderlecht 0-0 Dinamo Moscow
Gol:
Celtic 3-3 Inter Milan
Gol: Stuart Armstrong 24', Hugo Campagnaro 26' (og), John Guidetti 90' - Xherdan Shaqiri 5', Rodrigo Palacio 13', 45'
Guingamp 2-1 Dynamo Kyiv
Gol: Claudio Beauvue 73', Mustapha Diallo 75' - Miguel Veloso 19'
Kartu merah: Andriy Yarmolenko 40', Younes Belhanda 45' (Dynamo Kyiv)
Liverpool 1-0 Besiktas
Gol: Mario Balotelli 85' (pen)
Sevilla 1-0 Borussia Moenchengladbach
Gol: Vicente Iborra 70'
Tottenham Hotspur 1-1 Fiorentina
Gol: Roberto Soldado 6' - Jose Maria Basanta 36'
Villarreal 2-1 Salzburg
Gol: Ikechukwu Uche 32', Denis Cheryshev 54' - Jonathan Soriano 48' (pen)